Pulmonary Arterial Hypertension - Gilead Initiates Letairis® (ambrisentan) Phase IV Program

Posted by poster on July 15th, 2008 under Uncategorized Tags: ,  •  Comments Off

Gilead Sciences, Inc. (Nasdaq: GILD) today announced the initiation of
ATHENA-1, a Phase IV, randomized, double-blind, placebo-controlled study evaluating Letairis®
(ambrisentan 5 mg and 10 mg tablets) in patients with pulmonary arterial hypertension (PAH)
demonstrating a sub-optimal response to sildenafil monotherapy. ATHENA-1 is the first of several
Phase IV Letairis studies Gilead plans to initiate in 2008 and 2009. Read the rest of this entry »

Studies Show Workplace Depression Is Significantly Under-Treated

Posted by poster on July 15th, 2008 under Uncategorized Tags: , ,  •  Comments Off

The Journal of Environmental and Occupational Medicine (JOEM) has published a series of new studies that suggest depression in the workplace may be a much bigger problem - with more serious social and economic impacts - than employers realize.
The peer-reviewed journal has devoted an entire special-edition, titled "Depression in the Workplace," to the topic, Read the rest of this entry »

Immune System Pathway Identified To Fight Allergens, Asthma

Posted by poster on July 14th, 2008 under Uncategorized Tags:  •  Comments Off

For the first time, researchers from the University of Pittsburgh School of Medicine have identified genetic components of dendritic cells that are key to asthma and allergy-related immune response malfunction. Targeting these elements could result in more effective drugs to treat allergic disorders and asthma, according to a study reported Read the rest of this entry »

House Of Lords To Debate Science Committee Allergy Report, UK

Posted by poster on July 14th, 2008 under Uncategorized Tags: ,  •  Comments Off

The House of Lords will on Thursday 8 May debate the Science and Technology Committee’s report on Allergy which was published in September last year.
The Government responded to the report in November and accepted many of the Committee’s recommendations. The Read the rest of this entry »

BrainCells Inc. Initiates Phase 2 Clinical Trial With BCI-540 For Depression With Anxiety

Posted by poster on July 14th, 2008 under Uncategorized Tags: ,  •  Comments Off

BrainCells Inc. (BCI), a
biopharmaceutical company utilizing its platform technology to identify and
develop compounds that promote the growth of new neurons for the treatment
of central nervous system (CNS) diseases, announced that it has
initiated a Phase 2a clinical trial with its lead product candidate,
BCI-540, for the treatment of depression Read the rest of this entry »

Correlation Between Erectile Dysfunction And LUTS The AUA Lecture

Posted by poster on July 12th, 2008 under Uncategorized Tags: , , ,  •  Comments Off

UroToday.com - Dr. Kevin McVary (Chicago) presented the AUA lecture. The incidence of ED increases to over 60% by age 60. He showed data that ED increases with increasing severity of LUTS, independent of age. Across all age groups, increasing LUTS correlated with worse ED even Read the rest of this entry »

Cleviprex(TM) Reduces And Controls Acutely Elevated Blood Pressure In Elderly Patients, According To New Analysis From VELOCITY Trial

Posted by poster on July 12th, 2008 under Uncategorized Tags: , ,  •  Comments Off

The Medicines Company (NASDAQ: MDCO) announced that its investigational agent, CleviprexTM (clevidipine butyrate) injectable emulsion was well tolerated in elderly patients and rapidly achieved and maintained blood pressure control in patients presenting to the emergency department or intensive care unit with acutely elevated blood pressure (n=27), according to a post-hoc analysis Read the rest of this entry »

Post-Traumatic Stress Disorder Associated With More, Longer Hospitalizations

Posted by poster on July 11th, 2008 under Uncategorized Tags: ,  •  Comments Off

Researchers from Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) have found post-traumatic stress disorder (PTSD) is associated with more hospitalizations, longer hospitalizations and greater mental healthcare utilization in urban primary care patients. These findings appear in the current issue of Medical Care.
Prior studies suggest that trauma exposure and PTSD have considerable impact on health care use and costs. Read the rest of this entry »

High Blood Pressure Still Sneaking Past Doctors, Stanford Study Shows

Posted by poster on July 11th, 2008 under Uncategorized Tags: , , , , ,  •  Comments Off

Despite the well-known dangers of high blood pressure, major shortfalls still exist in the screening, treatment and control of the disease even when patients are getting a doctor’s care, according to a study from the Stanford University School of Medicine.
In a unique look at how blood pressure, or hypertension, is being addressed once a patient steps into a doctor’s Read the rest of this entry »

Scientists cast doubt on value of screening for prostate cancer

Posted by poster on July 11th, 2008 under Uncategorized  •  Comments Off

Men’s Health News
Even though deaths from prostate cancer death have fallen in the U.S. since screening became more common, new research is suggesting that this does not justify the need for such tests.
According to a team of scientists from the University of Bristol many other factors could be involved such as different Read the rest of this entry »

Pharmacopeia Announces Upcoming Late-Breaker Presentation Of Phase 2a Results For Its First-in-Class Investigational DARA Compound, PS433540

Posted by poster on July 10th, 2008 under Uncategorized Tags:  •  Comments Off

Pharmacopeia
(Nasdaq: PCOP), an innovator in the discovery and development of novel
small molecule therapeutics, announced that results from the
company’s Phase 2a clinical trial evaluating PS433540, its first-in-class
Dual Acting Receptor Antagonist (DARA), will be presented as a
late-breaking clinical trial at the American Society of Hypertension (ASH)
Twenty-Third Annual Scientific Meeting and Exposition Read the rest of this entry »

Tight Blood Pressure Control Not Enough To Temper Kidney Disease In African Americans

Posted by poster on July 10th, 2008 under Uncategorized Tags: ,  •  Comments Off

Even when their blood pressure is kept strictly under control with the best available medicine, African-American patients with chronic kidney disease (CKD) continue to lose their kidney function over time, research led by a Johns Hopkins team shows. The finding suggests that treating CKD in this population may be vastly more complex than researchers had previously thought, with blood pressure control being only one piece of the therapeutic Read the rest of this entry »

Management Of High Blood Pressure Immediately After Stroke

Posted by poster on July 10th, 2008 under Uncategorized Tags: , ,  •  Comments Off

A research project at the University of Leicester in conjunction with the University of East Anglia, indicates that early reduction of high blood pressure following stroke is feasible and safe, and both Labetalol & Lisinopril were found to be suitable a medications for this purpose.
Larger studies will now be necessary to confirm this result and test the effects on recovery Read the rest of this entry »

Better Hypertension Treatment By Determining How The Body Regulates Blood Pressure In Response To Daily Stress

Posted by poster on July 9th, 2008 under Uncategorized Tags: , , , , ,  •  Comments Off

How the body regulates blood pressure in response to daily stress is the focus of a study geared toward helping people whose pressure is out of control.
"Research shows that two-thirds of patients’ high blood pressure is not controlled despite the best efforts of their doctors. That is terrible," says Dr. Gregory Harshfield, director of the Georgia Prevention Institute Read the rest of this entry »

Two Men Fined For Selling Erectile Dysfunction Drugs, UK

Posted by poster on July 9th, 2008 under Uncategorized Tags: , , , , , , , ,  •  Comments Off

Latest News For This Category
Correlation Between Erectile Dysfunction And LUTS The AUA Lecture
19 Apr 2008
A Mixed
Set Of Results From 5-Alpha-Reductase Inhibitors And Reduced Prostate Cancer Risk
16 Apr 2008
Federal Authorities Seize More Than 100,000 Dollars Of Read the rest of this entry »

Perrigo Announces Approval For Over The Counter Children’s Cetirizine Oral Solution

Posted by poster on July 9th, 2008 under Uncategorized Tags: ,  •  Comments Off

Perrigo Company
(Nasdaq: PRGO; TASE) announced that it has received final approval
from the U.S. Food and Drug Administration to manufacture and market
over-the-counter (OTC) Children’s Cetirizine Hydrochloride Oral Solution
(Allergy) and Children’s Cetirizine Hydrochloride Oral Solution
(Hives-Relief), 1mg/mL.
The product will be marketed under store brand labels and is comparable
Read the rest of this entry »

A Call For Standardized Measurement Of Outcomes In Depression Treatment

Posted by poster on July 8th, 2008 under Uncategorized Tags: , ,  •  Comments Off

Rhode Island Hospital and Brown University researchers are calling on clinicians to adopt a standardized measurement of outcomes when treating depression. The commentary was published in the June edition of Primary Psychiatry.
Researchers led by Mark Zimmerman, M.D., noted that quantified measurement of outcome is rarely done when treating depression, yet to determine the impact of treatment it Read the rest of this entry »

JNC Bases New Guidelines For Hypertension Treatment With Diuretics On Research

Posted by poster on July 8th, 2008 under Uncategorized Tags: , , ,  •  Comments Off

A study based at The University of Texas Health Science Center at Houston provides added justification that a thiazide-type diuretic is the best first-choice drug for hypertensive patients. The findings, published in the American Heart Association’s Circulation, Volume 117, Issue 20, evaluate the results of a previous trial coordinated by researchers at The University of Texas Read the rest of this entry »

Four Innovative Novartis Medicines For Cancer, Asthma, High Blood Pressure And Wet AMD Approved In Japan

Posted by poster on June 29th, 2008 under Uncategorized Tags: , , ,  •  Comments Off

Patients in Japan stand to benefit from the approval of four innovative medicines - Tasigna® for the treatment of a life-threatening form of leukemia, Xolair® for severe asthma, Co-Dio® for high blood pressure, and Lucentis® for wet age-related macular degeneration (AMD), an eye disease that is a major cause of blindness in people over the age of 50 in Japan.
"It is a significant achievement Read the rest of this entry »

SSRIs May Reduce Suicide In Adults

Posted by poster on June 27th, 2008 under Uncategorized Tags: , ,  •  Comments Off

Selective serotonin reuptake inhibitors (SSRIs) may reduce the risk of suicide in depressed adults, according to a study by researchers from the World Health Organization and the University of Verona, Italy published in CMAJ.
The study, a meta-analysis of 8 large-scale observational studies, was undertaken to explore whether SSRIs reduce or increase the Read the rest of this entry »

Link Between Less Severe First Heart Attacks And Heart Disease Death Reductions

Posted by poster on June 15th, 2008 under Uncategorized Tags: ,  •  Comments Off

The severity of first heart attacks has dropped significantly in the United States - propelling a decline in coronary heart disease deaths, researchers reported in Circulation: Journal of the American Heart Association.
"This landmark study suggests that better prevention and better management in the hospital have contributed to the reduction in deaths," said Merle Read the rest of this entry »

Chronic Pain Might Contribute To Suicidal Thoughts

Posted by poster on June 8th, 2008 under Uncategorized  •  Comments Off

New research suggests that patients with chronic pain are more prone than others are to consider suicide. The increased risk remained even when study authors took the possible influence of mental illness into account.
"This is further evidence that we need to be aware of the heightened risk for suicide in those with chronic pain," said Mark Ilgen, lead study author. "More work is needed to figure out who’s going to be at the Read the rest of this entry »

Gender Difference In Severity Of Rheumatoid Arthritis

Posted by poster on June 2nd, 2008 under Uncategorized Tags:  •  Comments Off

Women appear to suffer more from rheumatoid arthritis (RA) than men. This is revealed in research published in BioMed Central’s open access journal Arthritis Research and Therapy.
Tuulikki Sokka from the Jyvaskyla Central Hospital, Finland, along with other members of the Quantitative Standard Monitoring of Patients with RA (QUEST-RA) program, explored possible associations between gender and disease activity measures, treatments, and Read the rest of this entry »

Newer Blood Pressure Drug Shows Promise As Alternative To ACE Inhibitors For Some Patients

Posted by poster on June 1st, 2008 under Uncategorized Tags: ,  •  Comments Off

Researchers in Canada working on an international study, discovered that the angiotensin-receptor blocker (ARB) telmisartan, a newer type of
drug for lowering blood pressure, showed a modest reduction in cardiovascular deaths, strokes and heart attacks in patients with heart problems and
diabetes who can’t tolerate the standard and more widely used angiotensin-converting-enzyme (ACE) inhibitors.
The research Read the rest of this entry »

NY City Health Department Launches Effort To Study Neighborhood Air Quality

Posted by poster on May 27th, 2008 under Uncategorized  •  Comments Off

The Health Department today announced the launch of the New York City Community Air Survey, the first comprehensive effort to monitor street level air pollution in neighborhoods across the five boroughs. Air pollution monitors mounted on 150 light posts throughout the city will be used to measure major air pollutants that contribute to health problems. The data collected will help the city better understand how pollution from traffic, buildings, and other sources affects Read the rest of this entry »